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OncoNano Medicine, Inc.

BiotechnologyBiotechnologyMedical DevicesCancer Therapeutics
πŸ“ Dallas, TX, United Statesβ€’ Founded 2014β€’ 22 employees
StreetZero Signal 78
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About OncoNano Medicine, Inc.

OncoNano Medicine, Inc. is a Dallas, Texas-based biotechnology company and spinoff from UT Southwestern Medical Center that develops pH-responsive fluorescent nanoprobes and polymeric micelle platforms for real-time tumor visualization during surgery and targeted cancer therapeutics. Its lead imaging agent, pegsitacianine (TT1-L1N3), exploits acidic tumor microenvironments to glow under near-infrared light, improving resection accuracy in preclinical models of breast and pancreatic cancers. The company also advances ONM-501, a STING agonist therapeutic, and the ON-BOARD delivery platform for precise payload delivery to tumors. It operates as a privately held B2B entity focused on product sales in the medical devices and biotechnology sectors.

LATEST FUNDINGPrivate Placement
$10.1M
Announced 2026-10-08
TOTAL RAISED$188M
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Key highlights

  • Raised ~$50M Series B led by Advantech Capital to advance pegsitacianine and ONM-501.
  • CPRIT converted $18.4M in grants into equity investment in 2021 for clinical development.
  • Developing pH-responsive nanoprobes that improve tumor margin visualization in surgery.
  • Entered research collaboration with Gilead using ON-BOARD platform for drug delivery.
  • Total funding reached ~$188M across 7 rounds including grants and equity.

Source document & SEC filing

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